This timely volume serves as both an introduction and a fundamental reference for scientists interested in learning about or applying genomic,proteomic and metabolomic technologies to surrogate tissue analysis. Various scientists at the cutting edge of these fields review both the fundamental analytical issues and the initial results generated using these technologies to date. One of the first publications to describe this approach, the book covers transcriptional profiling (genomics), protein profiling (proteomics), methylation profiling (epigenomics), metabolite profiling (metabolomics) and additional screening methods that can be applied to surrogate tissues. This book is a useful reference text for researchers and scientists interested in applying novel methodologies for identifying biomarkers in the fields of pharmacology, toxicology and medicine. ..

This timely volume serves as both an introduction and a fundamental reference for scientists interested in learning about or applying genomic,proteomic and metabolomic technologies to surrogate tissue analysis. Various scientists at the cutting edge of these fields review both the fundamental analytical issues and the initial results generated using these technologies to date. One of the first publications to describe this approach, the book covers transcriptional profiling (genomics), protein profiling (proteomics), methylation profiling (epigenomics), metabolite profiling (metabolomics) and additional screening methods that can be applied to surrogate tissues. This book is a useful reference text for researchers and scientists interested in applying novel methodologies for identifying biomarkers in the fields of pharmacology, toxicology and medicine. ..